The relationship between serum adiponectin level and chronic inflammation,atherosclerosis in maintenance hemodialysis patients.
- VernacularTitle:维持性血液透析患者血清脂联素水平与慢性炎症 动脉粥样硬化关系的研究
- Author:
Zhongxin LI
;
Juan MENG
;
Liren PENG
- Publication Type:Journal Article
- Keywords:
maintenance hemodialysis;
atherosclerosis;
adiponectin
- From:
Chinese Journal of Practical Internal Medicine
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the relationship between serum adiponectin level and chronic inflammation,atherosclerosis in maintenance hemodialysis(MHD)patients.Methods Totally 60 MHD patients and 30 healthy volunteers were included in this study.Serum adiponectin level(ADPN)and C-reative protein(CRP),interleukin-6(IL-6)were measured.Carotid initial-medial thickness(IMT)and brachial arterial vasodilation were determined by echocardiography.Results Serum ADPN level(0.99?0.37)was higher in MHD patients than that(0.39?0.14)in controls.The ADPN level of higher IMT group was lower than that in normal IMT group.CRP,IL-6 and Cartid IMT were negatively correlated with ADPN(r=-0.22,-0.31-0.26,P