Clinical value of combined detection of high sensitive C reactive protein and blood lipids in coronary heart disease
10.3760/cma.j.issn.1673-4130.2009.10.011
- VernacularTitle:超敏C反应蛋白与血脂联合检测在冠心病中的临床价值
- Author:
Lanlan LI
;
Ganqing TU
- Publication Type:Journal Article
- Keywords:
C-Reactive Protein;
Dyslipidemias;
Coronary Disease;
Fibrinogen
- From:
International Journal of Laboratory Medicine
2009;30(10):963-964,978
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of high sensitive C reactive protein(hs-CRP)and blood lipids,and investigate the clinical value of combined detection of the above markers in evaluating the risk and prognosis of coronary heart disease(CHD).Methods Totally 51 cases of stable angina pectoris(SAP group),44 cases of unstable angina pectoris(UAP group),40 cases of acute myocardial infarction(AMI group)and 45 healthy controls(healthy control group)were enrolled in the investigation.Hs-CRP and blood lipids were measured with enzymic method and immunoturbidimetry respeetively.Results The level of hs-CRP was significantly higher in UAP group and AMI group than that in healthy control group(both P＜0.05).Hs-CRP level was a little higher in SAP group than that in healthy control group,but there was no statistical difference(P＞0.05).In addition,hs-CRP was positively correlative with total cholesterol(TC),low density lipoprotein-cholesteroK LDL-C),apoprotein B (apoB)and lipoprotein a(LPa)(P＜0.05),and negatively correlative with high density lipoproteincholesterol(HDL-C)and apoAI(P＜0.05).Conclusion Hs-CRP contributes to diagnosis of CHD,and combined detection of hs-CRP and blood lipids is of important value in evaluating the risk and prognosis of CHD.
