Aminophylline or doxapram attenuates somnolence induced by postoperative intravenous analgesia with butorphanol
- VernacularTitle:氨茶碱和多沙普仑减轻布托啡诺术后镇痛期嗜睡的比较
- Author:
Zhaoping ZHANG
;
Xiaofeng GU
;
Guohua SUN
;
Zhengzheng ZHANG
- Publication Type:Journal Article
- Keywords:
aminophylline;
doxapram;
butorphanol;
combination;
analgesia;
side-effect
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the altion of aminophylline or doxapram attenuate somnolence induced by postoperative intravenous analgesia with butorphanol.METHODS: One hundred and five adult patients were randomly divided into three groups under epidural blockade.0.01% butorphanol and 0.25% aminophylline analgesia-pump(groupⅠ,n=35),0.01% butorphanol and 0.15% doxapram analgesia-pump(groupⅡ,n=35),and 0.01% butorphanol analgesia-pump(group Ⅲ,n=35).Lethargy and analgesia effect were compared.RESULTS: The analgesia effects were satisfactory in the three groups after operation.conscious-sedation score(OAA/S)(at 8-24 h after operation)in groupⅢ was higher than those in groupⅠand Ⅱ(P