Effect of iron overload on bone mass density and the change of micronutrients
- VernacularTitle:铁负荷过度对骨密度和微量营养素变化的影响
- Author:
Yuanyuan ZHUANG
;
Yinghui YU
;
Ying ZHANG
;
Lin MENG
;
Ting ZHAO
;
Wenjun DING
;
He LI
;
Rong JIANG
;
Haibo CHEN
- Publication Type:Journal Article
- Keywords:
Iron overload;
Bone mass density;
Vitamin;
Homocysteine;
Blood lipid;
Trace element
- From:Parenteral & Enteral Nutrition
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the change of bone mass density(BMD) and micronutrients in middle-aged and old patients with iron overload and the effect on levels of micronutrients.Methods: BMD was measured by dual energy X-ray absorptiometry(DXA) in 19 middle-aged and old patients with iron overload and 41 age-and gender-matched healthy subjects.Serum selenium(Se)was measured by fluorospectrophotometry.Serum zinc(Zn) was measured by inductively coupled plasma atomic emission spectrometry(ICP-AES).Plasma vitamin A,D and E were measured by HPLC.The levels of blood lipid and plasma homocysteine were measured by automatic biochemical analyzer.Results: Plasma vitamin E of 19 iron overload patients was significantly lower than control group,and the levels of triglyceride and homocysteine increased significantly(P
