Biological effect of four isoflavone derivatives on proliferation of endometrial epithelial cells in vitro
- VernacularTitle:4种异黄酮改构化合物对人离体子宫内膜腺上皮细胞增殖活性的比较
- Author:
Cheng CHEN
;
Qing CHANG
;
Lilong ZHANG
;
Guoping AI
- Publication Type:Journal Article
- Keywords:
isoflavone derivatives;
endometrial epithelial cells;
cells proliferation
- From:Journal of Third Military Medical University
2003;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the biological effects of four isoflavone derivatives(F8,F11,ZF3 and ZF7)on endometrial epithelial cells.Methods The endometrial epithelial cells were cultured through collagenase enzymatic digestion and twice grit filtration.The biological effects on endometrial epithelial cells of four isoflavone derivatives were compared through MTT.Results The primary endometrial epithelial cells were successfully disassociated,cultured and passaged down stably.Cell proliferation was significantly increased by F8(25 mol/L)(P