Endothelial glycocalyx and cardiovascular disease
- VernacularTitle:血管内皮细胞糖萼与心血管疾病
- Author:
Ke WEN
;
Pingnian HE
;
Jianshi LOU
- Publication Type:Journal Article
- Keywords:
glycocalyx;
endothelial cell;
cardiovascular disease
- From:
Chinese Pharmacological Bulletin
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Endothelial glycocalyx is a hairy-like structure covered the endothelial cell surface,which consists of multiple functional elements.It has been proved that glycocalyx can regulate vascular permeability,mediate shear-induced release of NO by endothelial cells,and exert wide array of vasculoprotective effects via inhibition of coagulation and leucocyte adhesion.Degradation of glycocalyx may be associated with many cardiovascular diseases.In this review,the relationship between the endothelial glycocalyx and cardiovascular disease will be discussed.
