Construction of psoriasis susceptibility gene
- VernacularTitle:银屑病易感基因HLA-Cw*0602的构建
- Author:
Jianping ZHU
;
Yuan YUAN
;
Xia LIU
;
Jingjing QI
- Publication Type:Journal Article
- Keywords:
psoriasis;
susceptibility gene;
HLA-Cw*0602
- From:
Chinese Pharmacological Bulletin
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To prepare for psoriasis transgenic animals, psoriasis susceptible gene was constructed. Methods Extract gDNA from blood preparations of psoriasis patients, screen positive gDNA owns HLA-Cw*0602 gene, then copy the whole sequence and link it to pMD-19T Simple Vector. Results The identification showed the construction of psoriasis susceptible gene was sucessful. Conclusion The successful construction of HLA-Cw*0602 gene will lay the foundation for development of transgenic animal models of psoriasis.
