Preparation and dissolution test of compound Yuxingcao dispersible tablets
- VernacularTitle:复方鱼腥草分散片的制备及其溶出度测定
- Author:
Xiaofang LI
;
Bohong GUO
;
Yongyin LI
- Publication Type:Journal Article
- Keywords:
Compound Yuxingcao dispersible tablet;
Formulations optimization;
Dissolution
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To prepare the compound Yuxingcao dispersible tablets and investigate the dissolution of baicalin in vitro. Methods: The formulation of dispersible tablets was optimized by an orthogonal design test in terms of disinterating time.Results: The optimal disintegrants were composed of CMS-Na 5%,MCC 20%,L-HPC 10%,and disintegration time of prepared compound Yuxingcao dispersible tablets followed the quality specification of dispersible tablet in Chinese Pharmacopoeia 2005. The in vitro dissolution test indicated that more than 95% of baicalin dissolved in 3 minute from dispersible tablets. Concolusion: The formulation and preparation process of compound Yuxingcao dispersible tablets were simple and feasible.
