Study on biological basis of phlegm and blood stasis syndromes in TCM
- VernacularTitle:中医痰浊血瘀证候的生物学基础研究
- Author:
Ling ZHAO
;
Haifeng WEI
;
Li ZHANG
;
Yali LI
;
Lin LI
- Publication Type:Journal Article
- Keywords:
High fat diet;
Blood lipid;
Hemorheology;
Blood vessel endothelium;
Blood stasis;
Phlegm;
Rat
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the biological basis of phlegm syndrome (Tan Zheng) and blood stasis syndrome (Xue-Yu Zheng) in traditional Chinese medicine(TCM) through the dynamic observation of the changes of blood lipid hemorheology and vessel endothelium impairment. Methods: SD rats were divided into fi ve groups randomly: the control group fed by normal diet, four model groups fed by 2-, 4-, 8- and 16-week high cholesterol diet, respectively. The indices of blood lipid hemorheology the level of plasma endothelin (ET) and serum nitric oxide (NO) were detected. Results: Compared with normal control group, serum total cholesterol (TC) and LDL-C levels raised signif icantly after being given hypercholesterol diet for 2 weeks, and this changes lasted till 16 weeks(P
