Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats
- VernacularTitle:二陈汤及桃红四物汤对非酒精性脂肪肝CYP2E1活性影响的实验研究
- Author:
Shujun LIU
;
Jingjuan HUANG
- Publication Type:Journal Article
- Keywords:
Non-alcoholic fatty liver;
cyp2e1;
Erchen decoction;
Taohongsiwu decoction;
Experimental study
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the therapeutic effects of Erchen decoction, Taohongsiwu decoction on CYP2E1 activity and microsome protein content in non-alcoholic fatty liver rats.Methods: Experimental animal model of non-alcoholic fatty liver rats were established , then treated with Erchen decoction, TaohongSiwu decoction.Microsome protein content and cyp2e1 activity are tested after treatment.Results: Microsome protein content of non-alcoholic fatty liver rats reduced and cyp2e1 activity increased. Compared with model group, in Erchen decoction group, the microsome protein content in hepatocyte increased significantly (P
