Comparison of the Efficacy of Nebulised Budesonide with Oral Prednisolone in Treatment of Idiopathic Pulmonary Fibrosis
- VernacularTitle:布地奈德吸入和口服泼尼松龙治疗特发性肺纤维化的疗效比较
- Author:
Hong ZHAO
;
Lixiang ZHANG
;
Qiang TIAN
- Publication Type:Journal Article
- Keywords:
Budesonide;
Prednisolone;
Idiopathic pulmonary fibrosis
- From:
Journal of Medical Research
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of nebulized budesonide and oral prednisolone in treatment of idiopathic pulmonary fibrosis(IPF).Methods Forty-two patients with IPF were randomized to divide into two groups,nebulised budesonide groups and oral prednisolone groups.Symptoms,signs,pulmonary function,arterial blood gases analysis and the adverse effects were measured.ResultsThere were significant improvement of VC and PaO2 of nebulized budesonide and oral prednisolone groups,but there were no significant differences between of nebulized budesonide groups and oral prednisolone groups.The adverse effects in nebulised budesonide group were obviously less than those in oral prednisolone groups.Conclusion Nebulized budesonide was an effective method in treatment of idiopathic pulmonary fibrosis.
