Effects of Resveratrol on Cell Morphology and Related Factors of Gastric Cancer Cell in vitro
- VernacularTitle:白藜芦醇对人胃癌MGC803细胞形态影响和相关增生因素的变化
- Author:
Rui WANG
;
Hongxin FEI
;
Zhihong GUO
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Resveratrol;
Cell cycle
- From:
Journal of Medical Research
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of resveratrol on cell morphology and related factors of gastric cancer cell line in vitro.Methods Drug sensitivity was detected by MTT assay.Changes of its biological characteristics were determined using light microscopy,electron microscopy cell counting by MTT assay,flow cytometry(FCM).Results Resveratrol(0.1g/L、0.2g/L)could arrest the suspended gastric cancer cell(MGC803)to S phase respectively.Resveratrol significantly inhibited growth and proliferation of MGC803 cells in dose-dependent manner.Conclusion Resveratrol(0.1g/L 、0.2g/L)may inhibit MGC803 cell growth.
