Protective effect of Sini decoction on acute myocardial ischemia in rats
- VernacularTitle:四逆汤对大鼠心肌缺血损伤的保护作用
- Author:
Jin HE
;
Yanwei FANG
;
Yongmin LI
- Publication Type:Journal Article
- Keywords:
Sini decoction;
Myocardial ischemia;
Isoprenaline;
Pituitrin
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the protective e ect of Sini decoction on experimental myocardial ischemia in rats.Methods:The model of acute myocardial ischemia in rats was induced by subcutaneous injection of isoprenaline and sublingual venous injection of pituitrin.The changes of ECG,serum activity of creatine phosphokinase(CPK),lactate dehydrogenase(LDH),aspartate aminotransferase(AST),malondialdehyde(MDA) and superoxide dismutase(SOD)were measured.Results:Sini decoction signi cantly improved the extents of abnormal rising and lowering of ST segment(P
