Correlativity of leptin,TNF-? with metabolic syndrome
- VernacularTitle:血清瘦素 肿瘤坏死因子-?与代谢综合征的相关性分析
- Author:
Xiaowen ZHAO
;
Hong QIAO
;
Yan LIU
- Publication Type:Journal Article
- Keywords:
leptin;
TNF-?;
metabolic syndrome
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relation of leptin,TNF-? in serum of patients with metabolic syndrome and its components.Methods Test leptin and TNF-? level of residents over 20 years old in two communities in Harbin City,grouping case-control study base on the constitutive ratio of actual age.Results Leptin was associated with obesity,and the higher leptin levels,the higher risk of suffering from metabolic syndrome.The relationship between leptin levels and metabolic syndrome was affected by age and gender.The lower level of TNF-?,the higher risk of metabolic syndrome.The patients with lower level of TNF-? were 1.859 times more likely to suffer from disease compared with people with higher level.Conclusion The effects of high level of leptin are significant on metabolic syndrome,especially for old males,and are associated with obesity component.TNF-? is related to plasma glucose and blood presure,and is good for metabolic syndrome,but its biological mechenism should be researched continuously.
