Expression of Bcl-2 and E2F-1 in Human Adenomyosis and Their Significance
- VernacularTitle:子宫腺肌病组织中Bcl-2、E2F-1蛋白的表达及其意义
- Author:
Ping CHEN
;
Lihong ZHENG
;
Feng LIU
- Publication Type:Journal Article
- Keywords:
Adenomyosis;
E2F-1;
Bcl-2;
Immunohistochemistry
- From:
Journal of Medical Research
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of Bcl-2 and E2F-1 in human adenomyosis and to explore the correlation between the expression and pathogenesis of human adenomyosis. Methods Immunohistochemical S-P method was employed to detect the expression of Bcl-2 and E2F-1 in 58 specimens of ectopic endometrium, eutopic endometrium of adenomyosis and 30 specimens of normal endometrium. Results The expression of Bcl-2 and E2F-1 in ectopic and eutopic endometrium of adenomyosis were significantly higher than those of normal endometrium (P