Lung Protection Due to Leukocyte-removed Priming Fluid Peri-cardiopulmonary Bypass in Infants
- VernacularTitle:去白细胞血预充对婴儿体外循环的肺保护作用
- Author:
Luyan GAO
;
Zimin CHEN
;
Tao WANG
- Publication Type:Journal Article
- Keywords:
Cardiopulmonary bypass;
White blood cell;
Lung protection
- From:
Journal of Medical Research
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of leukocyte-removed priming fluid on lung function peri-CPB in infants. Methods Selected 60 infants of less than 1-year-old, with ventricular septal defect (VSD), were randomly assigned to the experimental group and the control group, the experimental group took blood leukocyte-removed priming fluid, and the control group took banked blood-derived priming fluid. Indicators of OI, PaO2/PAO2, A-aDO2 and RI were recorded at the corresponding period of cardiopulmonary bypass (pre-CPB, 2h, 6h, 12h, 24h and 48h post-CPB). Results At 2h, 6h,12h post-CPB, OI and PaO2/PAO2 of the experimental group were higher than those of the control group (P