Expression and Significance of RXR_? in Gastric Carcinoma
- VernacularTitle:维甲类X受体RXR_?蛋白在胃癌组织中的表达及其临床意义
- Author:
Yanhong ZHOU
;
Lian DU
;
Shisheng LIU
- Publication Type:Journal Article
- Keywords:
RXR?;
Gastric cancer;
Superficial gastritis;
Normal mucosa
- From:
Journal of Medical Research
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the expression of RXR? gene protein in gastric cancer, superficial gastritis, normal gastric mucosa, in order to explore the relationship between the development of gastric cancer, combined with clinical and pathological analysis of its clinical significance. Methods Using immunohistochemical detection RXR? protein in gastric cancer, superficial gastritis, gastric mucosa in the normal expression. Results RXR? protein mainly located in the nucleus of cells, there are a small number of cytoplasmic staining, a brown or yellow granular, in gastric cancer, superficial gastritis, normal gastric mucosa, RXR? protein expression rates were 25.0%, 81.1%, 96.1%; group and the normal mucosa and superficial gastritis, gastric cancer group RXR? expression rate has dropped, there were significant differences (P0.05). The lymph node metastasis and tumor pathology and clinical phases closely related (P
