Serum levels of PAPP-A,IGF-1 in non-ST elevation acute coronary syndrome:report of 65 cases
- VernacularTitle:PAPP-A、IGF-Ⅰ在非ST段抬高的急性冠脉综合征患者中的临床意义
- Author:
Hongsheng LIU
;
Qinghua ZHANG
;
Zhixin JIANG
;
Ling PENG
;
Anquan LI
- Publication Type:Journal Article
- Keywords:
pregnancy associated plasma-A;
insulin-like growth factor-1;
non-ST elevation acute coronary syndromes
- From:Journal of Third Military Medical University
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the concentration of pregnancy associated plasma-A(PAPP-A),insulin-like growth factor-1(IGF-1)in indicating the instability of atherosclerotic plaques in patients with non-ST elevation acute coronary syndromes(NSTEACS).Methods Totally 65 patients with confirmed NSTEACS were subjected,including 30 non-ST elevation myocardial infarction(NSTEMI)and 35 unstable angina(UA)patients.Another 28 stable angina pectoris verified with vascular stenosis by coronary angiography(CAG)and 30 healthy matched individuals served as control.Serum levels of PAPP-A,C-reactive protein(CRP)and cTnT were measured respectively by enzyme linked immunosorbent assays(ELISA),rate nephelometry(RN),and microparticle enzyme immunoassay(MEIA).Correlation analysis was made among different groups.Results Serum PAPP-A,IGF-1 and CRP levels in NSTEACS group were significantly increased in comparison to SAP group and control group(P
