Clinical Significance of M K and VEGF Expression in Recurrent Gastric Carcinoma
- VernacularTitle:VEGF及中期因子在复发性胃癌中的表达及其临床意义
- Author:
Zhong JIA
;
Guanghua FENG
;
Qi XIE
;
Xin FANG
- Publication Type:Journal Article
- Keywords:
Gastric carcinoma;
MK;
Recurrence;
Tumor marker
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between midkine(MK) and VEGF expression with angiogenesis and biological features in recurrent gastric carcinoma.Methods The expression of MK was examined using immunohistochemistry in 9 cases of gastric carcinoma and 9 cases of adjacent normal tissues.Microvessel density(MVD)was determined by VEGF immunohistochemical staining.Results Majority of recurrent gastric carcinoma tissues showed positive reaction to immunostaining,but no specific positivity was detected in adjacent normal tissue.Values of MVD and MK positive group(88.8%,79.75) was higher than those in the negative group(15.0%)(P
