The clinical observation of the effect of mycophenolate mofetil combined with corticosteroid hormone on idiofocal segmental glomerular sclerosis.
- VernacularTitle:吗替麦考酚酯联合皮质类固醇激素治疗特发性局灶节段性肾小球硬化的临床观察
- Author:
Jing XIAO
;
Zhangsuo LIU
;
Zhanzheng ZHAO
;
Guolan XING
- Publication Type:Journal Article
- Keywords:
mycophenolate mofetil;
corticosteroid hormone;
focal segmental glomerular sclerosis
- From:
Chinese Journal of Practical Internal Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical curative effect and side-effect of MMF plus corticosteroid hormone compared with cyclophosphamide(CTX)plus corticosteroid hormone for idio-focal segmental glomerular sclerosis(I-FSGS).Methods Thirty patients with I-FSGS confirmed by renal biopsy in the Nephrology Department,the First Affiliated Hospital of Zhengzhou University from 2004 to 2006 were randomly divided into two groups-15 patients in each group:MMF combined with corticosteroid hormone as therapy group,and CTX combined with corticosteroid hormone as control group.The two groups were compared on urine protein in 24 hours,serum albumin and creatinine clearance rate(Ccr).Results There were significant differences(P
