Effects of Gypenosides on contraction of isolated duodenum smooth muscle of rabbits
- VernacularTitle:绞股蓝总皂苷对家兔离体十二指肠平滑肌收缩活动的影响
- Author:
Weiping ZHANG
;
Zhenghong LI
- Publication Type:Journal Article
- Keywords:
Gypenosides;
isolated duodenum;
contract
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To investigate the efftct of Gypenosides on contraction of isolated duodenum smooth mustle of rabbits.METHODS:The routine experimental method of isolated duodenal smooth muscle of rabbits were used.The contraction curves of isolated duodenum smooth mustle before and after administration of different concentrations of Gypenosides(0.01%-1.00%)were recorded by Medlab biological information collecting system.RESULTS:Different concentrations of Gypenosides significantly reduced the contraction amplitude of isolated duodenum smooth mustle of rabbits,and showed a dose-dependent relationship.CONCLUSION:Gypenosides can inhibit the contraction of isolated duodenum smooth muscle of rabbits.
