Effects of estrogen on estrogen receptors in myocardium of ovariectomized female rats
- VernacularTitle:雌激素对卵巢切除后雌性大鼠心肌组织中雌激素受体表达的影响
- Author:
Xiaohua ZHONG
;
Hui WANG
;
Qingping LI
- Publication Type:Journal Article
- Keywords:
estrogen receptor;
myocardium;
ovariectomy
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To investigate the expression of estrogen receptors in myocardium of ovariectomized female rats.METHODS:One week after bilateral ovariectomy,the female SD rats were divided into 3 groups randomly:OVX +estrogen(0.15 mg/kg,s.c.),OVX + normal sodium and control.After 4 weeks of treatment,the expression of estrogen receptors in the myocardium were evaluated by Western blotting.RESULTS:After ovariectomy,serum estrogen decreased significantly,compared with control[(88?22 vs 403?59)pmol/L,P
