Effects of stretch load on quantity and c-kit expression of rat bladder interstitial cells of Cajal
- VernacularTitle:牵张负荷对大鼠膀胱ICCs细胞数量及c-kit表达的影响
- Author:
Yang LU
;
Longkun LI
;
Yongquan WANG
- Publication Type:Journal Article
- Keywords:
stretch load;
interstitial cells of Cajal;
c-kit;
bladder
- From:Journal of Third Military Medical University
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of stretch load on the quantity of rat bladder interstitial cells of Cajal (ICCs) and c-kit expression in the cells. Methods Rat models of detrusor instability with partial outflow obstruction were established. The quantity of ICCs and c-kit expression in ICCs from stable, unstable and normal detrusor were studied with light microscopy and Western blotting. Results The quantity of ICCs and expression of c-kit in the stable and unstable detrusors were higher than that in normal control group (P
