Systematic review of randomized controlled trials on treatment of myocardial infarction with YiqiHuoxue Chinese patent medicine
- VernacularTitle:益气活血中成药治疗心肌梗死随机对照试验的系统评价
- Author:
Junhua ZHANG
- Publication Type:Journal Article
- Keywords:
Chinese patent medicine;
YiqiHuoxue;
Myocardial infarction;
Systematic evaluation
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the efficacy and safety of YiqiHuoxue preparations for the treatment of myocardial infarction(MI).Methods:An extensive search including Cochrane library,Medline,Embase,CBM,CNKI and VIP was performed up to November 2006.Randomized controlled trials(RCTs)about YiqiHuoxue Chinese patent medicine for the treatment of MI were included irrespective of language.The quality of each trial was assessed according to the Cochrane Reviewers'Handbook 4.2.6. Results:Twenty-eight RCTs were included in this review.The main outcomes were mortality,coronary artery recanalization, recurrent myocardial infarction,incidence of complications and other indirect outcomes.Because of the significant clinical heterogeneity between included trials,we just did descriptive analysis without meta-analysis.We couldn't get an affirmative conclusion that YiqiHuoxue preparations were useful for the treatment of MI.Conclusions:Because of low quality and significant heterogeneity of included trials,the efficacy of YiqiHuoxue Chinese patent medicine for the treatment of MI are still lack of sufficient evidence.Further studies are necessary.
