Effect of Chinese medicine Baoganning on lipid and serum leptin of liver fibrosis model rats
- VernacularTitle:中药保肝宁对肝纤维化大鼠血脂及血清瘦素的影响
- Author:
Songqi HE
;
Bin WEN
;
Liying HOU
;
Zhiping LV
- Publication Type:Journal Article
- Keywords:
Liver fibrosis;
Model rats;
TCM therapy;
Baoganning;
Lipid;
Leptin
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the mechanism of Baoganning anti-liver fibrosis.Methods:liver fibrosis rat models were established by complex factors.Automatic biochemical analyzer was used to detect TC、TG and RIA isotope analysis was used to detect serum leptin.To observe the influence of Baoganning on TC、TG and leptin level of liver fibrosis model rats. Results:Compared with the normal group,levels of serum TC,TG decreased apparently in model and every drug groups(P0.05).Conclusion:Baoganning can effectively prevent and treat liver fibrosis in rats,which may be closely related to the improvement of liver function,adjustment of lipid and reduction of serum leptin.