Influence of ulinastain on tumor necrosis factor and interleukin-6 in patients after cardiopulmonary resuscitation
- VernacularTitle:乌司他汀对心肺复苏术后肿瘤坏死因子及白细胞介素-6变化影响的研究
- Author:
Xiangmin LI
- Publication Type:Journal Article
- Keywords:
cardiopulmonary resuscitation;
tumor necrosis factor;
interleukin-6;
ulinastain
- From:
Chinese Journal of Practical Internal Medicine
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence of systemic inflammatory response syndrome(SIRS)after cardiopulmonary resuscitation(CPR)and to observe the effect of ulinastain in inhibition of inflammatory mediator.Methods Thirty-two patients surviving more than 72 hours after CPR were divided into ulinastain group and control group randomly.Activity of TNF-? and IL-6 of these patients was detected.In the meantime,all patients were evaluated by SIRS diagnosis and all data were compared between two groups.Results Activities of TNF-? and IL-6 in patients after CPR were significantly higher than that of normal people(P
