Association of adiponectin gene Gly15Gly polymorphism with primary macroangiopathy in diabetes mellitus
- VernacularTitle:脂联素基因Gly15Gly多态性与糖尿病大血管病变的关系
- Author:
Zhihua AI
;
Dianchun FANG
;
Zhonghui ZHANG
- Publication Type:Journal Article
- Keywords:
adiponectin;
gene polymorphism;
diabetes mellitus;
macroangiopathy
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association adiponectin gene polymorphism with primary macroangiopathy in diabetes mellitus. Methods Type 2 diabetes mellitus (T2DM) patients were included, 56 patients complicated with atherosclerosis (AS) and 120 non-AS group. We evaluated their Gly15Gly polymorphism of adiponectin gene by PCR restriction fragment length polymorphism (PCR-RFLP). Results The AS patients were more likely to have GG genotype than the non-AS patients (25.0% vs 6.2%, P
