Effect of Microecologics on the Intestinal Bacterial Overgrowth and Bacterial Translocation in Cirrhotic Rats
- VernacularTitle:微生态制剂对肝硬化大鼠肠道细菌过度生长及肠道细菌易位的影响
- Author:
Tianyan SUN
;
Huiji WANG
;
Qing YUAN
- Publication Type:Journal Article
- Keywords:
Cirrhosis of liver;
Intestinal bacterial overgrowth;
Endotoxin;
Bacterial translocation;
Microecologics
- From:
Journal of Medical Research
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the intestinal bacterial overgrowth(IBO)and bacterial translocation(BT)in cirrhotic rats,and the effect of microecologics on it.Methods In order to induce cirrhosis model the rats were given 40%CCl4 elaeo-solution by subcutaneous injection,then were treated by microecologics(prebiotics and probiotics).The rats were randomly divided into normal control group(13 rats),cirrhosis model group(10 rats),prebiotics therapy group(19 rats),probiotics therapy group(19 rats)and therapy control group(20 rats).To detect endotoxin,cultivate and count enteric bacilli.mesenteric lymph nodes,tissue of liver and spleen were taken to cultivate bacteria.Results ① the counts of small intestinal bacilli in cirrhosis rats were obviously higher than normal rats(P
