Advances in the effect of probiotics on gut barrier and microflora of experimental inflammatory bowel diseases
- VernacularTitle:益生菌对实验性炎症性肠病的肠屏障与微生态影响研究进展
- Author:
Hongqi CHEN
;
Huanlong QIN
- Publication Type:Journal Article
- Keywords:
Probiotics;
Inflammatory bowel disease;
Intestinal microflora;
Gut barrier
- From:
Parenteral & Enteral Nutrition
1997;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The aetiology of inflammatory bowel diseases(IBD) is still unknown at the present time.However,along with more and more experimental models of IBD developed in recent ten years,the therapeutic effect of probiotics on IBD and the possible mechanisms were widely explored.A lot of experiments have shown that probiotics administration can significantly ameliorate the IBD in many kinds of animal models and this beneficial effect of probiotics may be associated with inhibiting microbial growth,enhancing gut-barrier function,modulating immune response of intestinal mucosa and decomposing luminal pathogenic antigens.
