Effects of catgut implantation at acupoint on learning and memory and LTP of the vascular dementia model rats
- VernacularTitle:穴位埋线对血管性痴呆大鼠学习记忆和长时程增强的影响
- Author:
Can CHEN
;
Qiong YANG
;
Taoli DAI
;
Ya PAN
;
Xudong WANG
;
Min ZHANG
- Publication Type:Journal Article
- Keywords:
Vascular dementia;
Thread embedding;
Learning and memory;
Long term potentiation;
Dentate gyrus of hippocampus;
Experimental study
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of point thread embedding on the learning and memory of the vascular dementia(VD) model rats and the possible mechanisms. Methods: VD rat models were established by employing improved method of Pulsinelli's four-vessel occlusion,then the model rats were treated with point thread embedding.Morris maze test was used to evaluate the learning and memory of the rats.In vivo recording of long term potentiation(LTP) was performed in the dentate gyrus of hippocampus and changes in each experimental group were observed and compared after high-frequency stimulation(HFS).Results: Compared with models group,the results from the Morris tests in treated group(thread embedding group)enhanced significantly(P
