HPLC analysis of the constituents of Radix Puerariae absorbed into blood
- VernacularTitle:葛根血中移行成分高效液相色谱分析
- Author:
Mei ZHANG
;
Feng QIU
;
Xuejun XIE
;
Jing LIU
;
Xiao CHEN
- Publication Type:Journal Article
- Keywords:
Radix Puerariae;
HPLC fingerprint;
Serum Pharmacochemistry
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To sieve the bioactive constituents of Radix Puerariae,serum pharmacochemistry research was performed.Method: Based on the establishment of HPLC fingerprints of Radix Puerariae,the constituents absorbed into blood were determined by comparing the HPLC fingerprints of the methanol extracts,tested serum samples and blank serum sample.Results: Four compounds absorbed into blood were detected,among which two were original constituents of Radix Puerariae(including puerarin),the other might be metabolites of the original constituents.Conclusion: These four constituents absorbed into blood were possible bioactive components of Radix Puerariae.Further studies on them will help clarify the bioactive constituents and mechanisms of Radix Puerariae.
