Relationship of hs-CRP with the state of anxiety and depression in patients with acute coronary syndrome
- VernacularTitle:急性冠脉综合征焦虑抑郁与超敏C-反应蛋白关系的研究
- Author:
Meijing LI
;
Wenlin MA
;
Ying XU
;
Junmeng ZHANG
;
Dayi HU
- Publication Type:Journal Article
- Keywords:
acute coronary syndrome;
hs-CRP;
anxiety;
depression
- From:
Chinese Journal of Practical Internal Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of the presence and severity of anxiety and depression with the increased inflammatory activity,as marked by the serum levels of high sensitivity C reactive protein(hs-CRP)after acute coronary syndrome(ACS).Methods Serum hs-CRP levels were measured in 647 ACS patients within 36 hours after onset of event.Depression and anxiety were evaluated by self-reporting standardized questionnaire,using a validated Chinese version of Hospital Anxiety and Depression Scale(HADS)(14 items)within 7 days.Results In ACS patients,serum levels of hs-CRP(mg/L)were lower in those with anxiety than those in control group[(10.43?3.55)mg/L vs(13.19?4.90)mg/L,P0.05].Conclusion Presence and severity of depression is associated with increased activity of inflammation in patients with ACS;however,anxiety does not have such an association with inflammation in patients with ACS.
