The update research on selective PPAR? modulator in anti-diabetic treatment
- VernacularTitle:选择性PPAR?调节剂治疗糖尿病的研究新进展
- Author:
Yi HUAN
;
Zhufang SHEN
- Publication Type:Journal Article
- Keywords:
selective PPAR? modulator;
peroxisome proliferators activated receptor ?;
insulin sensitizer;
diabetes
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
PPAR? is a kind of nuclear receptors responsible for the regulation of glucose and lipid metabolisim and adipocyte difference,which is related with the pathogenesis of obesity,insulin resistance and type 2 diabetes mellitus.PPAR? agonists as insulin sensitizer have been used in the clinical treatment for type 2 diabetes for more than decades.Recently,with the further research plunging into the PPAR signaling pathway and insulin sensitizer,the recognition of this crucial nuclear receptor has been renewed and developed.The aim of this review is to report the update research outcomes.
