Haplotype Analysis of 9 STR_S Loci on Human Y Chromosome in Han Ethnic Group of Kunming City
- VernacularTitle:昆明地区汉族人群9个Y-STR_S基因座单倍型分析及其旁系亲子鉴定应用
- Author:
Dehua LIU
;
Qiang JING
- Publication Type:Journal Article
- Keywords:
Locus Y-STRs;
Haplotype;
Haplotype frequencies
- From:
Journal of Medical Research
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the haplotype diversity of DYS390、DYS393、DYS437、DYS438、DYS439、DYS447、DYS448、DYS460、H4 loci in 216 unrelated individuals in Han ethnic group of Kunming city,Yunnan province.Methods The DNA were extracted with Chloroform,phenol methods or Chelex-100 method.STR-PCR,Non-denaturing polyacylaminde gel electrophoresis and Sliver staining and ABI377 sequencer were carried out for study.216 undividuals were collected from Han ethnic group in Kunming city.Results 216 types of haplotype were detected from 9 STRS.Every haplotype frequence was detected at 0.0046,GD=1.00005934437,The lowest arrangement of the repeat units was detected at 0.0046.S E=1.25?10-9。Conclution The 9 Y-STRs loci of Kunming people are highly polymorphic and are powerful means in determination of identify and paternity for forensic practice.
