Expressions of BMP-2 and bFGF in synovial tissues of cacroiliac joint in the patients with active ankylosing spondylitis
- VernacularTitle:BMP-2和bFGF在强直性脊柱炎活动期骶髂关节滑膜组织中的表达
- Author:
Jianming LI
;
Tongwei CHU
;
Yue ZHOU
- Publication Type:Journal Article
- Keywords:
ankylosing spondylitis;
bone morphogenetic protein-2;
basic fibroblast growth factor
- From:Journal of Third Military Medical University
1983;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expressions of BMP-2 and bFGF in ankylosing spondylitis(AS)patients in active stage.Methods Five patients with active AS were admitted from July 2006 to March 2007,including 4 males and 1 female,with average age of 31.4 years.Five patients with pelvic fracture served as control,including 3 males and 2 females,with average age of 34.5 years.Using immunohistochemistry,the expressions of BMP-2 and bFGF were detected in the frozen synovial tissues of cacroiliac joint in active AS patients and in the pelvic fracture patients,and the results were compared by analyzing the gray scale of the pictures.Results The positive expressions of BMP-2 and bFGF in the synovial tissues of cacroiliac joint in the patients with active AS were stronger than those in pelvic fracture patients(P
