Confirmation of CUT OFF for Thyroid Stimulating Hormone in Screening of Neonatal Congenital Hypothyroidism
- VernacularTitle:新生儿甲状腺功能减低症筛查中促甲状腺激素切值的确定
- Author:
Bin WANG
- Publication Type:Journal Article
- Keywords:
Hypothyroidism;
Cut off of TSH;
Neonate
- From:
Journal of Medical Research
2006;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Used three different methods(ELISA、EFIA、Tr-FIA)to measurate concentration of thyroid stimulating hormone(TSH)in dried blood samples on filterpaper of 32 Uygur neonates again,that were collected two or three year ago.At the same time,collected dried blood samples on filterpaper from the 32 children.Measurated concentration of TSH in the dried blood samples and did clinical examination.The results revealed that there is definite error in different methods.Eliminating measure error,the cut off of mensurating congenital hypothyroidism with dried blood samples on filterpaper are as follows:It is negative,if the concentration of TSH in dried blood samples on filterpaper is≤10?U/ml.It is dubious,if the concentration of TSH in dried blood samples on filterpaper is 10~20?U/ml.These neonates will be counterchecked in definite time to diagnose.It is positive,if the concentration of TSH in dried blood samples on filterpaper is≥20?U/ml.
