STUDIES ON COMPONENTS WITH ANTIHYPERGLYCEMIC EFFECT OF MOMORDICA CHARANTIA L. POLYSACCHARIDES
- VernacularTitle:苦瓜多糖降血糖活性成分的研究
- Author:
Ying DONG
;
Huihui ZHANG
- Publication Type:Journal Article
- Keywords:
Momordica charantia L.;
alkali-extracted polysaccharides;
blood glucose;
glucose tolerance
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antihyperglycemic effect and the most effective com-ponent of Momordica charantia L. and its mechanism. Method Water-extracted and alkali-extracted Momordica charantia L. polysaccharides with different molecular weight on streptozotocin induced diabetes mellitus mice were carried out. The antihyperglycemic mechanism was preliminarily analyzed. Results Alkali-extracted Momordica charantia L. polysaccharides could lower blood sugar,improve glucose tolerance and increase the content of hepatic glycogen significantly at the dose of both 200 and 400mg/kg bw. The content of fructosamine was also lowered. Conclusion The component of alkali extracted Momordica charantia L polysacchaides with maximal molecular weight possessed the best antihyperglycemic effect.
