Effect of Ruiqi pill on neuronal calcium level of cerebral cortex in brain of rat embryos
- VernacularTitle:睿祺片对胎鼠大脑皮层神经元内钙离子水平的影响
- Author:
Peiyun ZHOU
;
Wenjin GE
- Publication Type:Journal Article
- Keywords:
Ruiqi pill;
Improving memory;
Calium;
Cerebral cortex;
Neuron
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
To explore the effect of Ruiqi pill on neuronal calcium level of cerebral cortex in brain of rat embryos.Methods: The cerebral cortex of rat embryos pregnanted for 16-17 days were dissected.The neural cells were divided into Ruiqi pill group and control group randomly after 4-5 days in vitro culture.Effect of Ruiqi pill on neuronal calcium level of primary culture of cortical neurons in rat embryos was measured by laser scanning confocal microscopy.Results:Ruiqi pill could reduce neuronal calcium concentration,no change was found in the control group.Conclusion: Ruiqi pill reduced neuronal calcium concentration,which might be one of the mechanisms of Ruiqi pill in improving memory function.