The efficacy of losartan combined with amiodarone in cardioversion of atrial fibrillation and maintenance of sinus rhythm in patients with paroxysmal atrial fibrillation
- VernacularTitle:氯沙坦联合胺碘酮对阵发性心房颤动复律及复律后窦性心律维持的影响
- Author:
Xuegang YU
;
Yusheng XI
;
Bo XIAO
;
Lei ZHONG
;
Xiantian LUO
- Publication Type:Journal Article
- Keywords:
atrial fibrillation,cardioversion;
amiodarone;
losartan
- From:
Chinese Journal of Practical Internal Medicine
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of losartan combined with amiodarone in cardioversion of atrial fibrillation(AF)and maint of sinus rhythm in patients with paroxysmal AF.Methods From January 2003 to October 2005,a total of 86 consecutive patients with paroxysmal AF in 421 Hospital of PLA were randomly dividid into two group:group A(amiodarone,n=44)and.group B(amiodarone plus losartan n=42).The conversion of atrial fibrillation in 24 h,3 d and 7 d after therapy was investigated.The left atrial diameter was measured with transthoracic echocardiogram at before and after 6,12-months of treatment andyzed up to 12 months.Results The rate of cardioversion of AF is significantly higher in group A than group B at 7 d(86.36% vs 95.23%,P
