Rapidly Aggravated Creutzfeldt-Jacob Disease: Autopsy-Proven Case.
10.3348/jkrs.2005.53.5.331
- Author:
Seung Hyun PARK
1
;
Hyun Koo KANG
;
Hyeon YU
;
Sang Chun LEE
Author Information
1. Department of Diagnostic Radiology, Seoul Veterans Hospital, Korea.
- Publication Type:Case Report
- Keywords:
Brain;
Brain, MRI;
Brain, infection
- MeSH:
Brain;
Creutzfeldt-Jakob Syndrome;
Dementia;
Diffusion;
Humans;
Myoclonus;
Neurodegenerative Diseases;
Prion Diseases
- From:Journal of the Korean Radiological Society
2005;53(5):331-335
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Creutzfeldt-Jakob disease (CJD) is one of the transmissible spongiform encephalopathies, which is mediated by what has been known as "prion". It is a rare and fatal progressive neurodegenerative disease that affects the middle and old aged. There are a number of subtypes of CJD, one of which is the sporadic type characterized by rapidly progressing clinical symptoms, including progressive dementia, myoclonic jerk, and pyramidal or extrapyramidal syndrome. Patients usually end up dying within 1 to 2 years of contacting the disease. We report an autopsy-proven case of sporadic CJD with clinical symptoms that progressed within several days, along with dramatic changes on diffusion weighted magnetic resonance images.
