Study on the Genotyping of Aminoglycoside Modifying Enzymes Genes from Pan-drug Resistant Acinetobacter Baumannii.
- VernacularTitle:泛耐药鲍曼不动杆菌氨基糖苷类修饰酶基因研究
- Author:
Xiaomao QIAN
;
Yaling WAN
;
Haiyong JIN
- Publication Type:Journal Article
- Keywords:
Pan-drug resistant;
Acinetobacter baumannii;
Aminoglycoside modifying enzymes;
Genes
- From:
Journal of Medical Research
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the genotyping of aminoglycoside modifying enzymes on Pan-drug resistant A..baumannii(PDRA)isolated.Methods The antibiotic susceptibility of 16 different antibiotics of A.baumannii were tested by K-B method,aminoglycoside modifying enzymes coding genes of A.baumannii were detected by PCR.Results The detection rates of OXA-23group were 41.8%and aminoglycoside modifying enzymes coding genes of aac(3)-Ⅰ,aac(6')-Ⅰand ant(3″)-Ⅰ were 64.1%,64.1% and 74.4%.Conclusions The study showed that it is more serious for PDRA carrying aminoglycoside modifying enzymes coding genes.