Effect of Xuesaitong on lower limb of rabbit ischemia-reperfusion free radical
- VernacularTitle:血塞通对兔下肢缺血再灌注自由基信号的影响
- Author:
Jiqian LIU
;
Rongshu AN
;
Xianrong SHANG
;
Jianchun CAO
;
Gang CAO
;
Zhaohui CHEN
- Publication Type:Journal Article
- Keywords:
Total saponins of sanchi(Xuesaitong);
Free radical;
Electron spin resonance;
Experimental study
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the protective effect of Xuesaitong(total saponins of sanchi) on lower extremity ischemical reperfusion injury.Methods: To observe PBN-spin bulky adducts signal of lower extremity ischemical reperfusion of rabbit by using electron spin resonance technology and electron spin resonance promoter N-tert-butyl-2-phenylnitrone(PBN).Results: The signal intensity is correlated with time,compared with ischemia for 2 hours,the signal intensity of ischemia for 4 hours increased apparently.Xuesaitong would quench PBN-spin bulky adducts signal significantly.Conclusion: Xuesaitong have protective effect on lower extremity ischemia-reperfusion injury.
