Clinical features of aged male patients with hyperinsulinemia
- VernacularTitle:老年男性高胰岛素血症患者的临床特点分析
- Author:
Yanyan LI
;
Hui TIAN
;
Chunlin LI
- Publication Type:Journal Article
- Keywords:
hyperinsulinism;
insulin resistance;
metabolic syndrome
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features of aged men with hyperinsulinemia, and to explore its influence factors. Methods 521 aged persons belonging to the high-risk population of diabetes mellitus (DM) were given 75g oral glucose tolerance test (OGTT), and then divided into hyperinsulinemia group and normal insulin group according to the plasma insulin levels. Clinical features, glucose metabolism state, constituent ratio, complicating diseases, ? cell function and insulin resistance were compared between the two groups. Insulin resistance was determined by HOMA-IR, and ? cell function was determined by HOMA-?. The relationship between glycometabolic change and body weight was analyzed in hyperinsulinemia patients for a period of 2-10 years. Results 195 cases were in hyperinsulinemia group, and 326 cases were in normal insulin group. Compared with the latter, the subjects in hyperinsulinemia group showed higher values of BMI, waistline, fasting blood glucose (FBG), postprandial glucose (2hPBG), and systolic and diastolic blood pressure (SBP, DBP)(P
