Application of PLGA in the research of bone tissue-engineering
- VernacularTitle:PLGA缓释材料在骨组织工程研究中的应用
- Author:
Xijiang ZHAO
;
Xinsheng QI
- Publication Type:Journal Article
- Keywords:
bone;
tissue-engineering;
poly lactic-co-glycolic acid;
growth factors
- From:
International Journal of Biomedical Engineering
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Poly lactic-co-glycolic acid (PLGA) has been attracting increasing attention in the field of bone tissue engineering because it is a biodegradable polymer with excellent biocompatibility, controllable aperture and porous rate, and a degradation rate which is suitable for bone regeneration, and moreover a suitable carrier for the sustained release of growth factors. This article reviewed the recent research progress in PLGA as a material for controlled drug delivery with emphasis on how to make the scaffold more suitable for the regeneration of the bone and which is the better way to apply sustained release of growth factors embedded in the material in bone tissue engineering. It pointed out that PLGA carrying different growth factors will become the focal point in the field of bone tissue-engineering.
