The structure and function of KCNQ1 channel
- VernacularTitle:KCNQ1通道的结构和功能
- Author:
Hongjuan JING
;
Guangyuan HE
- Publication Type:Journal Article
- Keywords:
KCNQ1;
LQTS;
SQTS
- From:
Chinese Pharmacological Bulletin
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
The paper concluded systematically the progress of study on KCNQ1 in recent years.Firstly,the structure of ? subunit or ? subunit and its interaction between each other were explained in the paper.Secondly,the physiological function of complex KCNQ1/KCNE was interviewed,such as many kinds of inherited cardiac arrhythmias induced by mutation of KCNQ1 or KCNE and secretion of KCNQ1 in different epithelial cells.Eventually,the paper introduced the study of antagonists and agonists on KCNQ1 channel.
