H_3N_2 subtype of human influenza pneumonia with staphylococcal sepsis and staphylococcal pneumonia:Report of one case
- VernacularTitle:H_3N_2型人流行性感冒合并金黄色葡萄球菌败血症及金黄色葡萄球菌肺炎1例
- Author:
Xiangdong MU
;
Guangfa WANG
;
Chengli QUE
;
Guilian LI
- Publication Type:Journal Article
- Keywords:
Influenza;
Staphylococcus aureus;
Hemorrhagic septicemia;
Pneumonia, staphylococcal
- From:
Journal of Peking University(Health Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the clinical characteristics, diagnosis and therapy of influenza pneumonia with staphylococcal infection. One patient in our hospital was diagnosed and the literatures on the subject were reviewed. The patient presented with high fever and dyspnea. Arterial gas analysis indicated type 1 respiratory failure. Chest X ray photographs showed bilateral infiltrations and bilatera encapsulated pleural effusions. Viral separation and culture of pharyngeal swab indicated H3N2 subtype of human influenza virus. Blood, sputum and bronchoalveolar lavage fluid (BALF) cultures showed Staphylococcus aureus. Pleural effusion was complex parapneumonic pleural effusion. After the administration of anti-virus, anti-staphylococcal antibiotics and pleural cavity drainage, the patient was cured. The infection of staphylococcus aureus is a typical characteristic of influenza pneumonia, and anti-staphylococcal antibiotic therapy (with MRSA activity in MRSA endemic regions) should be initiated in hospitalized cases of influenza pneumonia. If complex parapneumonic pleural effusion or empyema complicated, we should perform pleural cavity drainage in time. The oral neuraminidase inhibitor (oseltamivir) could significantly improve prognosis.
