Relationship between serum IGF-Ⅱand peripheral neuropathy in type 2 diabetics.
- VernacularTitle:血清胰岛素样生长因子-Ⅱ与2型糖尿病外周神经病变的关系研究
- Author:
Li LIANG
;
Chengjiang LI
;
Bei ZHANG
- Publication Type:Journal Article
- Keywords:
Diabetes,non-insulin-dependent;
Peripheral neuropathy;
Insulin-like growth factor-Ⅱ
- From:
Chinese Journal of Practical Internal Medicine
2006;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the possible relationship between IGF-Ⅱand peripheral neuropathy in type 2 diabetes.Methods Seventy-one type 2 diabetic patients without peripheral neuropathy(Group A),Seventy-seven patients with peripheral neuropathy(Group B)and thiry healthy subjects(Group C)were recruited.Serum IGF-Ⅱwas determined in all subjects.Other clinical parameters(fasting plasma glucose、fasting plasma insulin,et al)and nerve conduction velocity were determined in Group A and Group B.Results Group B had significantly lower levels of IGF-Ⅱ,compared to GroupA and Ⅲ(P
