Outcome analysis of invasive fungal infections in patients with hematologic malignancy after micafungin treatment
- VernacularTitle:米卡芬净治疗恶性血液病合并侵袭性真菌病的疗效分析
- Author:
Bingxin ZHOU
;
Jianzhen SHEN
;
Yanjuan LIN
- Publication Type:Journal Article
- Keywords:
Fungal disease;
Micafungin;
Hematological malignancy
- From:
Chinese Journal of Practical Internal Medicine
2006;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of micafungin sodium for injection in the treatment of invasive fungal infections in patients with hematologic malignancy.Methods The therapeutic effect,action time and adverse effect were analyzed in 12 cases of invasive fungal infections in patients with hematologic malignancy who underwent intravenous injection of micafungin sodium 100 mg qd in Research Center of Hemotology,Union Hospital affiliated to Fujian Medical University,from February 2007 to October 2007.Results The total effective rate was 66.7%.The effective rates of the patients with clinical diagnosis and with recommended diagnosis were 57.14% and 80% respectively ;there was no significant difference between them.The mean action time was 1~5 days.Conclusion Micafungin sodium for injection is effective and safe in treatment of invasive fungal infections in patients with hematological malignancy.
