Giant Intrathoracic Meningocele and Breast Cancer in a Neurofibromatosis Type I Patient.
10.3340/jkns.2016.59.6.650
- Author:
Hridayesh Pratap MALLA
1
;
Bong Jin PARK
;
Jun Seok KOH
;
Dae Jean JO
Author Information
1. Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Neurofibromatosis;
Meningocele;
Breast cancer
- MeSH:
Arm;
Breast Neoplasms*;
Breast*;
Chromosomes, Human, Pair 17;
Congenital Abnormalities;
Female;
Humans;
Incidence;
Meningocele*;
Middle Aged;
Neurofibromatoses*;
Neurofibromatosis 1*;
Scoliosis
- From:Journal of Korean Neurosurgical Society
2016;59(6):650-654
- CountryRepublic of Korea
- Language:English
-
Abstract:
Intrathoracic meningoceles are relatively rare entities found in patients with neurofibromatosis type I (NF1). Given that both the BRCA1 and NF-1 genes are located on the same long arm of chromosome 17, one would expect concurrence of neurofibromatosis and breast cancer. However, incidence of such co-disorders is very rare in the literature. Here, the authors report a case of a 50-year-old female patient with NF-1 and concurrent cancer of the left breast, who had a huge bilobulated intrathoracic meningocele with thoracic dystrophic scoliosis, treated surgically via a posterior-only approach for the meningocele and spinal deformity in the same setting.
