Influence of lung inflation on arterial spin labeling signal in MR perfusion imaging of human lungs
- VernacularTitle:肺组织膨胀程度对动脉自旋标记MRI肺灌注的影响
- Author:
Li FAN
;
Shiyuan LIU
;
Xiangsheng XIAO
;
Xueyuan XU
- Publication Type:Journal Article
- Keywords:
lung;
perfusion,regional;
arterial spin labeling;
magnetic resonance imaging;
lung inflation
- From:
Academic Journal of Second Military Medical University
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the influence of lung inflation on MR perfusion imaging of human lung using an arterial spin labeling sequence called flow sensitive alternating inversion recovery(FAIR).Methods:Coronal perfusion-weighted images were obtained at different respiratory phases from 10 healthy volunteers on a 1.5T whole body scanner(GE medical system)using FAIR sequence.The changes of tagging efficiency of pulmonary parenchyma(?SI %),pulmonary blood flow and area of the scanning slice of different respiratory phases were analyzed.Results:(1)Significant difference was found in ?SI% between different respiratory phases(right lung P=0.021 5,left lung P=0.008 4),with that at end expiration greater than that at end inspiration.(2)Significant difference was also found in pulmonary blood flow at different respiratory phases(right lung P=8.92?10-5,left lung P=0.000 2),with that at end expiration higher than that at end inspiration.(3)The areas of the scanning slice were also significantly different at different respiratory phases(right lung P=2.94?10-5,left lung P=0.000 5),with that at end inspiration larger than that at end expiration.Conclusion:Pulmonary blood flow during expiration is higher than that during inspiration,which might be due to the decreased lung volume and increased vascular density during expiration.
